Foundational Data Initiative for Parkinson's Disease
We see enormous opportunity in the translation of genetic factors to a functional understanding of Parkinson's disease (PD) by unbiased data driven approaches. We will create a public atlas of molecular phenotypes derived from induced pluripotent stem (iPS) lines with a broad range of genetic risk. These data will define molecular networks that are perturbed in disease, providing disease insight, therapeutic targets and relevant readouts for interventional testing. Our intent is to be flexible, changing and augmenting assays, endpoints as needed/requested.