FOUNDIN-PD
Foundational Data Initiative for Parkinson's Disease
Conceptual Framework
We see enormous opportunity in the translation of genetic factors to a functional understanding of Parkinson's disease (PD) by unbiased data driven approaches. We will create a public atlas of molecular phenotypes derived from induced pluripotent stem (iPS) lines with a broad range of genetic risk. These data will define molecular networks that are perturbed in disease, providing disease insight, therapeutic targets and relevant readouts for interventional testing. Our intent is to be flexible, changing and augmenting assays, endpoints as needed/requested.
Objectives

FOUNDIN-PD is part of The Michael J. Fox Foundation’s PATH to PD program. Learn more at www.michaeljfox.org/pathtopd

Peter Heutink, Ph.D.
High content molecular assays and iPS lines

Steve Finkbeiner, M.D., Ph.D.
High content imaging

Kendall van Keuren Jensen, Ph.D.
Transcriptomics, RNA analysis
David W. Craig, Ph.D.
Data Integration, Bioinformatics
